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WCNDD and Ono Pharmaceutical Publish Key TREK Channel Study

Posted by on Tuesday, April 29, 2025 in News.

A new publication from the long-standing collaboration between WCNDD and Ono Pharmaceutical highlights a best-in-class in vivo tool compound targeting TREK ion channels. This study provides the first proof-of-concept for TREK activators as non-opioid analgesics and TREK inhibitors as pro-cognitive agents. Now featured among the most read in ACS Medicinal Chemistry Letters, the work marks a significant milestone in the partnership’s 12-year effort to advance novel CNS therapeutics.

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